An improved 62Zn/62Cu generator based on a cation exchanger and its fully remote-controlled preparation for clinical use
T Fukumura, K Okada, H Suzuki, R Nakao… - Nuclear medicine and …, 2006 - Elsevier
OBJECTIVE: The goal of this study was to develop an improved 62Zn/62Cu generator based
on cation exchange resin and remote preparation at high radioactivity scale for clinical use.
METHODS: A natural Cu target was irradiated with proton beam in the energy range of 30→
19 MeV at a beam current of 10 μA for 1 h to obtain around 1.7 GBq of 62Zn. The 62Zn was
isolated from the Cu target on an anion exchange column with more than 97% yield within
2.5 h from the EOB. The 62Zn/62Cu generator was prepared by loading the 62Zn2+ on a …
on cation exchange resin and remote preparation at high radioactivity scale for clinical use.
METHODS: A natural Cu target was irradiated with proton beam in the energy range of 30→
19 MeV at a beam current of 10 μA for 1 h to obtain around 1.7 GBq of 62Zn. The 62Zn was
isolated from the Cu target on an anion exchange column with more than 97% yield within
2.5 h from the EOB. The 62Zn/62Cu generator was prepared by loading the 62Zn2+ on a …
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